Parameter | 4-Bromo-2-pyridinemethanol | 2-Pyridinemethanol | 5-Bromo-2-pyridinemethanol |
---|---|---|---|
CAS Number | 223021-83-2 | 3430-13-5 | N/A |
Molecular Formula | C6H6BrNO | C6H7NO | C6H6BrNO |
Purity Grade | ≥98% (HPLC) | ≥95% | ≥97% |
Pharmaceutical Intermediates: Key precursor in HIV protease inhibitors and kinase inhibitor synthesis.
Catalyst Ligands: Coordination chemistry applications in asymmetric catalysis (hydrogenation reactions).
Material Science: Building block for functionalized polymers and metal-organic frameworks (MOFs).
Handling Requirements:
Case 1: Palladium-catalyzed cross-coupling reactions achieving 89% yield in anti-cancer compound synthesis.
Case 2: Chiral resolution agent development reducing enantiomer separation time by 40%.
Pharma Company A: (NYSE: PHA) Reduced intermediate synthesis steps from 5 to 2 in antiviral drug production.
Chemical Manufacturer B: Achieved 15% cost reduction in catalyst production through improved bromopyridine derivatives.
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