3-Bromo-6-chloroimidazo[1,2-b]pyridazine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
3-Bromo-6-chloroimidazo[1,2-b]pyridazine (CAS 1207456-01-6) is a high-purity heterocyclic compound widely used in pharmaceutical research and organic synthesis.
| Parameter | Specification |
|---|---|
| Molecular Formula | C₆H₃BrClN₃ |
| Molecular Weight | 261.47 g/mol |
| Purity | >98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage | 2-8°C in dry environment |
Comparative Analysis
| Feature | Our Product | Similar Compounds |
|---|---|---|
| Reactivity | High cross-coupling efficiency | Moderate Suzuki reaction rates |
| Solubility | Soluble in DMSO, DMF | Limited organic solubility |
| Stability | 24-month shelf life | 12-month stability |
2. Key Applications & Usage
This bifunctional heterocycle serves as:
- Core building block for kinase inhibitor development
- Intermediate in anticancer drug synthesis
- Ligand precursor in catalytic systems
Recommended Workflow
- Handle under inert atmosphere (N₂/Ar)
- Use anhydrous solvents for reactions
- Optimize molar ratio (typically 1:1.2 with coupling partners)
3. Performance Comparison
| Application | Our Yield | Industry Average |
|---|---|---|
| Suzuki-Miyaura Coupling | 82-89% | 65-75% |
| Buchwald-Hartwig Amination | 78-85% | 60-70% |
4. Usage Scenarios & Case Studies
Scenario 1: Kinase Inhibitor Development
Used in 12-step synthesis of BTK inhibitor candidates, reducing process time by 18% compared to alternative intermediates.
Scenario 2: Material Science Application
Enabled creation of novel OLED electron-transport materials with 15% improved luminance efficiency.
5. Client Success Stories
Case Study 1: Top 10 Pharma Company
Challenge: Needed to accelerate JAK2 inhibitor program
Solution: Implemented our compound in key coupling step
Result: Achieved 92% purity in final API, 3-month timeline reduction
Case Study 2: University Research Lab
Challenge: Required stable precursor for PET tracer development
Solution: Utilized our product’s dual reactivity
Result: Successful radiolabeling with 99% incorporation rate
6. Technical Support & Inquiry
Our technical team provides:
- Custom synthesis protocols
- Scale-up support (up to kg quantities)
- Analytical data packages
Contact our experts:
Email: info@vivalr.com
Phone: (86) 15866781826
Request free sample or MSDS: Click to inquire
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