4-Methoxy-3-nitropyridine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
4-Methoxy-3-nitropyridine (CAS 1074-85-3) is a nitro-substituted pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C6H6N2O3 |
| Molecular Weight | 154.12 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | Pale yellow crystalline powder |
Comparative Analysis
| Compound | 4-Methoxy-3-nitropyridine | 3-Nitropyridine |
|---|---|---|
| Reactivity | Moderate (methoxy group stabilizes) | High |
| Application Scope | Pharma intermediates, ligands | Basic nitration reactions |
2. Key Applications
Pharmaceutical Intermediates
Used in synthesizing kinase inhibitors and antiviral agents due to its electron-deficient aromatic ring.
Agrochemical Synthesis
Critical for producing herbicides and fungicides with enhanced bioavailability.
3. Usage Guidelines
Handling & Storage
- Store at 2-8°C in airtight containers
- Use nitrile gloves and PPE during handling
Reaction Optimization
Typical conditions for Suzuki coupling:
| Parameter | Value |
|---|---|
| Catalyst | Pd(PPh3)4 |
| Temperature | 80°C |
4. Case Studies
Anticancer Drug Intermediate
Used in 3-step synthesis of EGFR inhibitors, achieving 72% overall yield with >99% purity.
5. Client Success Stories
PharmaCorp (Germany)
Reduced production costs by 18% through optimized coupling reactions using our product.
AgroSolutions Inc. (USA)
Developed a novel fungicide formulation with 40% higher field efficacy.
6. Contact for Queries
Email: info@vivalr.com
Tel: (86) 15866781826
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