1. Product Overview & Specifications

1-Acetylpiperazine (CAS 5925-76-0) is a nitrogen-containing heterocyclic compound with molecular formula C₆H₁₂N₂O. It serves as a critical intermediate in pharmaceutical synthesis and specialty chemicals.

Technical Parameters

2. Key Applications & Functional Uses

Pharmaceutical Intermediate

Used in synthesis of antipsychotics (e.g., Aripiprazole) and antidepressants through nucleophilic substitution reactions.

Organic Synthesis

Acts as catalyst in Buchwald-Hartwig aminations and ligand in transition metal catalysis for C-N bond formation.

3. Operational Case Studies

1. Antiviral Drug Synthesis: Achieved 92% yield in Remdesivir intermediate preparation via optimized acetylation protocol.
2. Polymer Modification: Enhanced thermal stability (ΔT_g +28°C) in epoxy resins through piperazine-ring crosslinking.

4. Verified Client Implementations

Case 1: Top 10 Pharma Manufacturer

Client: Jiangsu Hengrui Pharmaceuticals
Application: Aprepitant antiemetic production scale-up
Result: Reduced reaction steps from 5 to 3, 18% cost savings

Case 2: Agrochemical Leader

Client: Syngenta AG
Application: Fungicide molecular stabilization
Result: Increased field efficacy duration by 40%

5. Technical Inquiry & Ordering

Contact our chemical engineering team for:

• Custom synthesis protocols
• Bulk pricing (100kg+ quantities)
• Regulatory documentation support

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