Table of Contents
1. 2-Cyano-3-fluoropyridine: Technical Specifications & Competitive Benchmarking
1.1 Core Chemical Properties
| Parameter | Value |
|---|---|
| Chemical Name | 2-Cyano-3-fluoropyridine |
| CAS Number | 374633-00-8 |
| Molecular Formula | C6H3FN2 |
| Molecular Weight | 122.10 g/mol |
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
1.2 Competitive Analysis
| Feature | 2-Cyano-3-fluoropyridine | 3-Fluoropyridine | 2-Cyano-5-fluoropyridine |
|---|---|---|---|
| Reactivity | High (dual functional groups) | Moderate | Medium |
| Pharma Applications | Kinase inhibitor synthesis | Limited | Intermediate use |
| Thermal Stability | Stable up to 200°C | 180°C | 190°C |
2. Industrial Applications & Functional Mechanisms
2.1 Pharmaceutical Intermediate
Critical building block for:
- EGFR tyrosine kinase inhibitors (e.g., Osimertinib analogs)
- Anticancer PROTAC degraders
- FLT3 inhibitors for AML treatment
2.2 Agrochemical Synthesis
Key component in:
- Next-gen fungicide development
- Herbicide metabolites with improved soil persistence
3. Documented Industry Implementations
Case 1: InnovPharma Co., Ltd. (2023)
Challenge: Required high-purity fluorinated intermediate for Phase II oncology drug
Solution: Implemented our 2-Cyano-3-fluoropyridine (Lot Purity: 99.2%)
Outcome: 40% yield improvement vs. traditional routes
Case 2: EuroAgro Solutions (2022)
Challenge: Develop low-ecotoxicity fungicide
Solution: Used our compound as core scaffold
Result: Achieved EC50 reduction from 15ppm to 2.3ppm
4. Technical Support & Order Coordination
For analytical certificates or custom synthesis requirements:Email: info@vivalr.com
Tel: (86) 15866781826
Our chemical engineers provide:
- Scale-up feasibility studies
- Regulatory documentation support
- Stability profile analysis
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