2-Amino-3,5-dibromo-4-methylpyridine

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2-Amino-3,5-dibromo-4-methylpyridine: Comprehensive User Guide

1. Product Overview & Specifications

Chemical Profile

2-Amino-3,5-dibromo-4-methylpyridine (CAS: 131747-63-2) is a brominated pyridine derivative with the molecular formula C6H5Br2N2 and a molecular weight of 279.93 g/mol. This halogenated heterocyclic compound is widely used in pharmaceutical synthesis, agrochemical research, and materials science.

Key Specifications

Parameter Value
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Melting Point 142-145°C
Solubility Soluble in DMSO, DMF; slightly soluble in ethanol
Storage 2-8°C in airtight container

2. Applications & Use Cases

Pharmaceutical Intermediate

Used as a key building block in:

  • Kinase inhibitor development (e.g., EGFR inhibitors)
  • Anticancer drug candidates
  • Antimicrobial agents

Material Science

  • Ligand in transition metal catalysis
  • Precursor for OLED materials

Agrochemical Research

  • Herbicide intermediate
  • Fungicide development

3. Comparative Analysis

Compound Reactivity Cost Efficiency Stability
2-Amino-3,5-dibromo-4-methylpyridine High (dual bromine sites) $$$ Stable under inert atmosphere
3,5-Dibromopyridine Moderate $$ Light-sensitive
4-Methyl-2-aminopyridine Low $ Air-stable

4. Customer Case Studies

Case 1: Oncology Drug Development

Client: Top 10 Pharma Company (Confidential)

  • Application: Synthesized BTK inhibitor candidate
  • Result: Achieved 92% yield in Buchwald-Hartwig coupling
  • Scale: 15 kg batch production

Case 2: OLED Material Synthesis

Client: OLED Materials Co., Ltd. (South Korea)

  • Application: Electron transport layer material
  • Result: Enhanced device lifetime by 40%
  • Purity Requirement: 99.5% (met specification)

5. How to Order & Inquire

For technical specifications, bulk pricing, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

Our team provides:

  • 24h response time
  • GMP-grade custom synthesis
  • Regulatory support (REACH, FDA DMF)

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