3,5-Dibromopyridine: Comprehensive Product Guide for Industrial and Research Applications
Table of Contents
1. Product Overview and Specifications
CAS Number: 625-92-3
Molecular Formula: C5H3Br2N
Molecular Weight: 236.89 g/mol
Appearance: White to pale yellow crystalline powder
Purity: ≥98% (HPLC)
Comparative Analysis with Related Compounds
Parameter | 3,5-Dibromopyridine | 2-Bromopyridine | 3-Bromopyridine |
---|---|---|---|
Reactivity | High (dual bromine sites) | Moderate | Moderate |
Synthetic Flexibility | Excellent for cross-coupling | Limited | Moderate |
Pharma Applications | Widely used | Niche use | Intermediate |
2. Key Applications of 3,5-Dibromopyridine
2.1 Pharmaceutical Intermediates
Critical for synthesizing kinase inhibitors and antiviral agents via Suzuki-Miyaura couplings.
2.2 Agrochemical Development
Used in creating novel herbicides with enhanced environmental stability.
2.3 Material Science
Building block for conductive polymers and OLED materials.
3. Usage Scenarios and Case Studies
3.1 Palladium-Catalyzed Cross-Coupling
Reaction: 3,5-Dibromopyridine + Boronic Acid → Biaryl Compounds
Yield: 82-89% under optimized conditions
3.2 Nucleophilic Substitution
Efficient amination reactions for creating polycyclic nitrogen compounds.
4. Real-World Client Success Stories
Case 1: PharmaSynth Co., Ltd. (Shanghai)
Challenge: Required high-purity intermediate for Phase III cancer drug
Solution: Customized 3,5-Dibromopyridine (99.7% purity)
Outcome: Reduced synthesis steps by 40%, accelerated FDA submission
Case 2: AgroChem Solutions Inc. (Berlin)
Developed breakthrough fungicide using our compound as key building block.
5. Request a Quote or Technical Support
Contact our chemistry experts for:
- Bulk pricing (25kg+ orders)
- Custom synthesis options
- Regulatory documentation support
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