Parameter | 2-Amino-5-chloro-4-picoline | Similar Compounds |
---|---|---|
CAS Number | 2940-94-7 | N/A |
Molecular Formula | C6H6ClN2 | Varies by compound |
Purity | ≥98% | Typically 95-99% |
Applications | Pharma intermediates, agrochemicals | Limited scope |
Widely used in synthesizing antiviral agents and kinase inhibitors due to its unique halogenated pyridine structure.
Critical component in next-generation herbicides and fungicides, offering enhanced bioactivity vs. traditional chloropyridines.
Challenge: Low yield in Bruton's tyrosine kinase (BTK) inhibitor precursor synthesis
Solution: Optimized coupling reaction using 2-Amino-5-chloro-4-picoline at 60°C
Result: Yield increased from 42% to 68% with 99.5% HPLC purity
Project: Development of non-small cell lung cancer treatment
Usage: Key building block in third-generation EGFR inhibitor
Outcome: Achieved 94% selectivity in target pathway inhibition
Application: Novel wheat fungicide formulation
Result: 82% disease suppression at half dosage of commercial benchmarks
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Field | Details |
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Name | [Your Name] |
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