Parameter | THIENO(3 2-B)PYRIDIN-7-OL | Analog Compound A | Industry Standard |
---|---|---|---|
CAS Number | Not disclosed | N/A | - |
Purity Grade | ≥99.5% (HPLC) | 98.0-99.0% | ≥95% |
Molecular Formula | C₈H₅NOS | C₇H₄NOS | - |
Thermal Stability | Up to 250°C | 200°C | 180-220°C |
Key roles in kinase inhibitor synthesis for oncology treatments, demonstrating exceptional bioactivity in PI3K/AKT/mTOR pathway modulation.
Critical component in OLED electron transport layers (ETL) with measured efficiency improvements of 18-22% versus conventional materials.
Maintain under inert gas (Argon preferred) at 2-8°C with desiccant. Shelf life: 36 months in original packaging.
Recommended catalyst loadings of 0.5-1.2 mol% for cross-coupling reactions. Typical yields range 78-92% under optimized conditions.
Used as core scaffold in third-generation BTK inhibitors, achieving IC₅₀ values of 0.8-1.2 nM in preclinical models.
Key intermediate in Tau protein aggregation inhibitors currently in Phase II clinical trials.
Application: JAK/STAT pathway inhibitor development
Results: Reduced lead optimization time by 40% through improved synthetic routes
Application: Organic semiconductor development
Results: Achieved 21% improvement in charge mobility for flexible displays
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