2-Chloropyridine-N-oxide

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2-Chloropyridine-N-oxide Technical Guide

Table of Contents

Product Specifications & Comparative Analysis

Parameter 2-Chloropyridine-N-oxide Similar Compounds
CAS Number 2402-95-1 20295-64-1 (Hydrochloride salt)
Molecular Formula C5H4ClNO C5H5Cl2NO (Hydrochloride)
Molecular Weight 129.54 g/mol 166.00 g/mol (Hydrochloride)
Density 1.5 g/cm³ 1.27 g/cm³ (Hydrochloride)
Melting Point 67-70°C 140-142°C (Hydrochloride)
Boiling Point 453.5°C 317.1°C (Analogous derivatives)

Applications & Industrial Uses

Pharmaceutical Intermediate

Key precursor for antimicrobial agents (e.g., pyrithione derivatives) and dermatological formulations.

Agrochemical Production

Critical component in synthesizing Clodinafop-propargyl herbicides and plant growth regulators.

Organic Synthesis

Used in:

  • Coordination chemistry for catalyst development
  • Polymer modification reactions
  • Specialty chemical manufacturing

Synthesis & Manufacturing Process

Industrial production methods:

  1. Catalytic oxidation of 2-chloropyridine (CAS 109-09-1) using Na2WO4/H2O2 systems
  2. Immobilized peracid catalysis for improved yield (>94%)
  3. Continuous flow reactor configurations

Case Studies & Client Implementations

Case 1: Agrochemical Manufacturer

Client: Hubei Maoerwo Bio-Pharmaceutical
Application: Production of Clodinafop-propargyl intermediates
Outcome: 18% yield improvement through optimized oxidation protocols

Case 2: Specialty Chemical Producer

Client: Shanghai Dian Microbiological Technology
Application: Pharmaceutical-grade N-oxide derivatives
Outcome: Achieved 99.5% purity for GMP-compliant production

Safety & Regulatory Compliance

Parameter Specification
Hazard Codes Xi (Irritant)
Risk Statements R36/37/38 (Irritating to eyes/respiratory system/skin)
Safety Protocols Use PPE, adequate ventilation, and chemical-resistant gloves
Transport Classification UN 2811 (Toxic solids, organic)

Contact for Technical Consultation

For technical specifications, bulk pricing, or custom synthesis requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

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