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2-Fluoro-6-methylpyridine (CAS 407-22-7): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | 2-Fluoro-6-methylpyridine | Comparable Derivatives* |
|---|---|---|
| CAS Number | 407-22-7 | 374633-38-2 (2-Bromo-5-fluoro-6-methylpyridine) |
| Molecular Formula | C6H6FN | C6H5BrFN |
| Molecular Weight | 111.12 g/mol | 190.01 g/mol |
| Boiling Point | 140-141°C | N/A |
| Density | 1.077 g/mL | N/A |
| Refractive Index | 1.47 | N/A |
*Comparisons based on structurally similar pyridine derivatives.
2. Key Applications
2-Fluoro-6-methylpyridine serves as a versatile building block in:
- Pharmaceutical Intermediates: Synthesis of fluorinated drug candidates targeting CNS disorders.
- Agrochemical Research: Development of novel pesticides and herbicides.
- Material Science: Preparation of fluorinated ligands for catalytic systems.
- Academic Research: Studying fluorination effects on pyridine reactivity.
3. Usage Guidelines
Typical Workflow
- Storage: Keep in sealed containers at 2-8°C under inert gas.
- Handling: Use in fume hood with nitrile gloves and safety goggles.
- Reaction Example: Nucleophilic substitution with Grignard reagents at -78°C.
4. Safety & Handling
| Hazard | Precaution |
|---|---|
| Flammable (H227) | Avoid ignition sources |
| Skin Irritation (H315) | Wear chemical-resistant gloves |
| Eye Damage (H319) | Use face shield |
5. Client Case Studies
Case 1: Pharmaceutical Developer (Confidential)
Application: Synthesized fluorinated kinase inhibitors
Result: Achieved 92% yield in key coupling step
Case 2: University Research Team
Application: Studied electronic effects in catalysis
Result: Published in J. Org. Chem. (2024)
6. Contact for Technical Support
Email: info@vivalr.com
Tel: (86) 15866781826
Request custom synthesis or MSDS: Contact within 24hrs.
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