2-Cyano-3-nitropyridine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Properties
2-Cyano-3-nitropyridine (CAS 4214-74-8) is a high-purity heterocyclic compound with molecular formula C6H3N3O2 and molecular weight 149.11 g/mol. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥99% | 97-98% | 95-97% |
| Solubility | Soluble in DMF, DMSO | Partial solubility | Limited solubility |
| Storage | 2-8°C, dry | Room temperature | Refrigerated |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors and anticancer agents due to its electron-withdrawing nitro and cyano groups, enabling precise functionalization at C2 and C3 positions.
Agrochemical Development
Critical precursor for novel pesticides targeting GABA receptors, with 30% higher bioactivity compared to chloropyridine analogs.
3. Industry Case Studies
Case 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Challenge: Low yield (45%) in EGFR inhibitor synthesis
Solution: Optimized Buchwald-Hartwig amination using 2-Cyano-3-nitropyridine
Result: Yield increased to 82%, reduced side products by 60%
Case 2: Antiviral Research
Client: Biotech Startup (San Francisco)
Challenge: Poor solubility of HCV NS5A inhibitors
Solution: Structural modification using cyano-nitropyridine core
Result: LogP reduced from 4.2 to 2.8, clinical trial approval achieved
4. Technical Support & Inquiry
Request custom synthesis, bulk pricing, or MSDS:
info@vivalr.com
(86) 15866781826
Global shipping available | GMP-grade batches upon request
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