Table of Contents

Tetrahydropyran-4-carbaldehyde: Product Overview

Basic Specifications

Parameter Value
CAS Number 5464-75-9
Molecular Formula C₆H₁₀O₂
Molecular Weight 114.14 g/mol
Appearance Colorless to pale yellow liquid
Purity ≥98% (GC)
Boiling Point 195-197°C
Density 1.06 g/cm³

Comparative Analysis

Feature Tetrahydropyran-4-carbaldehyde Cyclohexanecarbaldehyde
Ring Stability High (oxygen-containing ring) Moderate
Reactivity Excellent for nucleophilic additions Limited functionalization
Pharma Compatibility Preferred for chiral synthesis Less versatile

Key Applications

Pharmaceutical Intermediates

Critical in synthesizing antiviral agents (e.g., HIV protease inhibitors) and oncology drugs due to its chiral center and stable tetrahydropyran ring.

Agrochemical Production

Used as a precursor for herbicides and fungicides requiring oxygenated heterocyclic structures.

Material Science

Enables creation of advanced polymers with enhanced thermal stability for electronic components.

Industry Case Studies

Case Study 1: Antiviral Drug Development

Client: Top 10 Global Pharma Company
Application: Synthesis of a novel HCV NS5A inhibitor
Result: 23% yield improvement vs. alternative aldehydes, reduced side reactions

Case Study 2: High-Performance Polymer

Client: Specialty Materials Manufacturer
Application: Crosslinking agent for aerospace-grade epoxy resins
Result: Achieved 165°C glass transition temperature (15°C improvement)

Request a Quote

Email: info@vivalr.com
Phone: (86) 15866781826

[Custom Synthesis Available] Submit your purity requirements (98%-99.9%), packaging needs (1kg-1000kg), and GMP/non-GMP specifications.

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