Parameter | Specification | Sigma-Aldrich | TCI Chemicals |
---|---|---|---|
CAS Number | 3417-87-4 | 3417-87-4 | 3417-87-4 |
Purity | ≥98% (HPLC) | 97% | 98.5% |
Packaging | 1kg, 5kg, Custom | 100g units | 500g units |
Critical component in kinase inhibitor synthesis with demonstrated efficacy in preclinical trials.
Preferred ligand for transition metal complexes in catalytic applications (Kd = 2.3 × 10-7 M).
Maintain at 2-8°C under inert atmosphere (argon preferred) with desiccant.
Optimal performance achieved at 0.1-0.3 molar equivalents in Pd-catalyzed cross-couplings.
Enhanced yield by 42% in CDK9 inhibitor synthesis through optimized stoichiometric ratios.
Improved electron transport properties in blue-emitting layers (CIE y reduced by 0.08).
Achieved 92% API purity in scale-up production (batch size: 150kg).
Developed novel MOF structures with 35% increased surface area using 6-Phenyl-2-pyridone.
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