1. Product Overview & Specifications

Supplier Comparison

2. Key Applications

• Pharmaceutical Intermediates: Critical precursor in synthesizing kinase inhibitors and antiviral agents.
• Agrochemicals: Building block for nitrogen-containing pesticides.
• Organic Synthesis: Versatile substrate for cross-coupling reactions (e.g., Suzuki-Miyaura).
• Material Science: Used in coordination chemistry for ligand design.

3. Usage Guidelines

Handling Precautions

• Use PPE (gloves, goggles) in ventilated areas
• Avoid contact with strong oxidizers
• Store away from moisture and light

Reaction Optimization

• Optimal temperature range: 80-120°C
• Compatible solvents: DMF, THF, DCM
• Typical reaction time: 4-12 hours

4. Case Studies

Case 1: Anticancer Drug Intermediate

A research team successfully synthesized a Bruton’s tyrosine kinase (BTK) inhibitor using 3-bromo-4-nitropyridine as the key intermediate, achieving 92% yield in Buchwald-Hartwig amination.

Case 2: Herbicide Development

In agrochemical R&D, this compound enabled the creation of a novel pyridine-based herbicide with 40% improved weed control efficacy compared to commercial benchmarks.

5. Client Success Stories

Pharma Company A (Shanghai)

• Used 500kg batch for COVID-19 protease inhibitor project
• Achieved 99.3% HPLC purity in final API
• Reduced synthesis steps from 8 to 5

Research Institute B (Boston)

• Developed novel ADC linker using 3-bromo-4-nitropyridine
• Published in Nature Chemistry (2024)
• Patent filed: US2024034567A1

6. Request a Quote

Contact our technical team for bulk pricing, SDS, or custom synthesis requirements:

info@vivalr.com
(86) 15866781826