Parameter | 2-Fluoro-6-formylpyridine | Similar Compounds |
---|---|---|
CAS Number | 374593-49-4 | N/A |
Molecular Formula | C6H4FNO | C6H5NO (Pyridine-2-carboxaldehyde) |
Molecular Weight | 125.10 g/mol | 107.11 g/mol |
Purity | >98% (HPLC) | 90-95% |
Storage | 2-8°C in dark | Room temperature |
Differentiation Factors: Enhanced electrophilicity from fluorine substitution enables superior reactivity in nucleophilic aromatic substitution compared to non-fluorinated analogs.
Widely utilized in synthesizing kinase inhibitors and antiviral agents through:
Critical component in novel pesticide synthesis:
Reaction Type | Recommended Conditions | Yield Range |
---|---|---|
Amine Condensation | EtOH, 60°C, 12h | 75-85% |
Cross Coupling | Pd(OAc)₂, K₂CO₃, DMF | 60-70% |
Application: JAK3 inhibitor development
Result: 40% improvement in binding affinity vs non-fluorinated analogs
Application: Next-gen herbicide formulation
Result: 3x faster degradation profile meeting EPA guidelines
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