2-Chloro-5-Fluoropyridine-4-Boronic Acid: Comprehensive User Guide

1. Product Overview & Parameter Comparison

Parameter 2-Chloro-5-Fluoropyridine-4-Boronic Acid Common Boronic Acids
CAS Number 1072951-77-6 Varies
Molecular Formula C5H3BClFNO2
Molecular Weight 193.35 g/mol 150-250 g/mol
Purity ≥97% (HPLC) 90-98%
Storage 2-8°C under inert gas Room temperature

2. Key Applications

This specialty boronic acid is widely used in:

  • Pharmaceutical Intermediates: Suzuki-Miyaura cross-couplings for API synthesis
  • Material Science: Building block for OLED materials
  • Agrochemicals: Creation of fluorinated pesticides
  • PET Tracers: Radiolabeling precursors

3. Usage Scenarios

Case 1: API Intermediate Synthesis

Reaction: Pd-catalyzed coupling with 3-bromopyridine
Conditions: DME/H2O (3:1), K2CO3, 80°C, 12h
Yield: 82-87%

Case 2: OLED Material Development

Application: Electron-transport layer component
Performance: Enhanced luminescence efficiency by 18% vs standard materials

4. Customer Case Studies

PharmaTech Solutions (Germany)

Challenge: Low-yield coupling in kinase inhibitor synthesis
Solution: Implemented our boronic acid in optimized Suzuki reaction
Result: Achieved 89% yield with 99.2% purity

AgroChem Co., Ltd (China)

Project: Novel fungicide development
Outcome: Reduced synthesis steps from 5 to 3 using direct coupling

Materials Innovation Inc (USA)

Breakthrough: Created thermally stable (280°C+) organic semiconductors

5. Inquiry & Contact

Request technical specifications or pricing:

Email: info@vivalr.com
Phone: (86) 15866781826

Custom synthesis available: Bulk quantities (1kg+) with 99%+ purity

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