2,6-Dichloropyridine N-Oxide: Technical Guide for Industrial Applications
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2,6-Dichloropyridine N-Oxide | Standard Pyridine Derivatives |
|---|---|---|
| CAS Number | 2587-00-0 | Varies by compound |
| Molecular Formula | C5H3Cl2NO | Typically C5H5N variants |
| Purity | ≥98% (HPLC) | 90-95% (average) |
| Thermal Stability | Stable up to 200°C | 150-180°C (typical) |
| HS Code | 29333990.90 | 29333990.xx |
2. Industrial Applications
Key Functional Roles:
- Pharmaceutical Intermediates: Precursor for antiviral/antibacterial APIs
- Agrochemical Synthesis: Building block for advanced pesticides
- Coordination Chemistry: Ligand in transition metal catalysis
- Polymer Modification: Surface functionalization agent
3. Operational Guidelines
Optimal Handling Parameters:
| Process Stage | Recommended Conditions |
|---|---|
| Storage | -20°C in inert atmosphere |
| Reaction Solvent | Dry DCM or THF |
| Catalytic Use | 0.5-2 mol% with Pd complexes |
| Safety Protocols | Class II ventilated hood required |
4. Case Studies
Case A: Pharmaceutical Intermediate Production
Challenge: Achieve >99% regioselectivity in nucleophilic substitution
Solution: 1.2 eq. 2,6-Dichloropyridine N-Oxide in DMF at 80°C
Outcome: 92% yield with 99.3% purity
5. Client Success Stories
Wuxi Life Science Biotech Co., Ltd.
Application: High-throughput synthesis of kinase inhibitors
Annual Usage: 15kg (GMP-grade)
Performance: Reduced reaction steps from 7 to 4 in API synthesis
6. Request Customized Solutions
Contact our technical team for batch optimization or custom synthesis:
Email: info@vivalr.com
Tel: (86) 15866781826
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