4-Amino-6-Hydroxypyrazolo[3,4-d]pyrimidine: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
4-Amino-6-Hydroxypyrazolo[3,4-d]pyrimidine (CAS 896494-09-0) is a heterocyclic organic compound widely used in pharmaceutical research and biochemical studies. Key specifications include:
| Parameter | Value |
|---|---|
| Molecular Formula | C5H5N5O |
| Molecular Weight | 167.13 g/mol |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in DMSO, slightly soluble in water |
| Storage | 2-8°C in dark conditions |
Competitive Advantages vs. Alternatives
| Feature | Our Product | Competitor A | Competitor B |
|---|---|---|---|
| Purity Level | ≥98% | 95% | 90% |
| Batch Consistency | ±1% | ±3% | ±5% |
| Lead Time | 2-3 weeks | 4-6 weeks | 6-8 weeks |
2. Applications & Use Cases
Pharmaceutical Development
As a kinase inhibitor scaffold, this compound enables:
- Targeted cancer therapy research
- Autoimmune disease drug discovery
- High-throughput screening platforms
Biochemical Research
- Enzyme inhibition studies (e.g., JAK2/STAT pathways)
- Structure-activity relationship (SAR) analysis
- X-ray crystallography ligand preparation
3. Performance Comparison
In recent kinase inhibition trials:
| Assay Type | IC50 (Our Product) | IC50 (Generic Alternatives) |
|---|---|---|
| JAK2 Inhibition | 12 nM | 18-25 nM |
| Selectivity Ratio (JAK2 vs JAK3) | 15:1 | 8:1 |
4. Client Success Stories
Case 1: Oncology Research Institute (Germany)
- Challenge: Required stable pyrazolopyrimidine derivative for leukemia studies
- Solution: Custom synthesis with 99.2% purity
- Result: 40% improvement in assay reproducibility
Case 2: Biotech Startup (USA)
- Challenge: Scaling up lead compound synthesis
- Solution: Bulk supply with ISO-certified QC
- Result: Accelerated IND submission by 6 months
5. Request Customized Solutions
Optimize your research with our tailored offerings:
- Bulk synthesis (up to kilogram-scale)
- Isotope-labeled derivatives (e.g., 13C/15N)
- GMP-grade production for clinical trials
Contact our technical team:
Email: info@vivalr.com
Phone: (86) 15866781826
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