4-Phenylpiperidine (CAS 771-99-3): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
4-Phenylpiperidine (CAS 771-99-3) is a heterocyclic organic compound widely used in pharmaceutical synthesis and chemical research. Below are its key specifications:
Parameter | Specification |
---|---|
CAS Number | 771-99-3 |
Molecular Formula | C11H15N |
Molecular Weight | 161.24 g/mol |
Purity | ≥98% (HPLC) |
Appearance | White to off-white crystalline powder |
Comparative Analysis
Feature | 4-Phenylpiperidine | Piperidine |
---|---|---|
Aromatic Substituent | Yes | No |
Reactivity | Moderate | High |
2. Key Applications & Uses
4-Phenylpiperidine serves critical roles in:
- Pharmaceuticals: Intermediate for CNS drugs, analgesics, and antipsychotics.
- Agrochemicals: Building block for pesticide formulations.
- Material Science: Ligand in catalytic systems.
3. Usage Scenarios & Best Practices
Scenario 1: Drug Synthesis
Used in multi-step synthesis of opioid receptor modulators under inert atmosphere.
Scenario 2: Catalytic Hydrogenation
Acts as a chiral auxiliary in asymmetric hydrogenation (1-5 mol% loading).
4. Customer Case Studies
Case Study 1: PharmaTech Solutions
Challenge: Scaling a Parkinson’s drug intermediate.
Solution: 4-Phenylpiperidine enabled 92% yield at GMP-grade purity.
Result: Accelerated Phase III trials by 6 months.
Case Study 2: AgroChem Ltd.
Challenge: Developing a low-toxicity fungicide.
Solution: Optimized synthesis using 4-Phenylpiperidine derivatives.
Result: Achieved EPA approval in 11 months.
5. Contact for Custom Solutions
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