Dioscin CAS 19057-60-4

Chemical Name: Dioscin
CAS No.: 19057-60-4
Appearance: White to off-white powder
Assay:98%HPLC

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Dioscin (CAS 19057-60-4) Ultimate User Guide

Table of Contents

1. Product Overview & Specifications

Dioscin (CAS 19057-60-4) is a natural steroidal saponin extracted from plants like Dioscorea species. Widely used in pharmaceuticals and nutraceuticals due to its bioactive properties.

Parameter Dioscin Similar Compounds
CAS Number 19057-60-4 Diosgenin: 512-04-9
Purity ≥98% (HPLC) ≥95% (Typical for saponins)
Solubility DMSO, Ethanol Varies by glycoside structure
Storage -20°C, desiccated Similar requirements

2. Key Applications of Dioscin

2.1 Anticancer Research

Inhibits proliferation of liver, breast, and colon cancer cells via apoptosis induction (Jiang et al., 2022).

2.2 Anti-inflammatory Formulations

Reduces TNF-α and IL-6 levels in arthritis models at 10-50 μM concentrations.

2.3 Cardiovascular Health

Shows 40% reduction in atherosclerotic plaque formation in murine studies.

3. Usage Scenarios & Best Practices

3.1 Pharmaceutical Development

Typical Workflow:
1. Dissolve in DMSO (10 mg/mL stock)
2. Test cytotoxicity (IC50 range: 5-20 μM)
3. Combine with paclitaxel for synergistic effects

3.2 Nutraceutical Manufacturing

Stable in capsule formulations with enteric coating (2-year shelf life at 25°C).

4. Client Success Stories

Case 1: BioPharm Solutions LLC (USA)

Challenge: Needed natural compound to enhance chemo sensitivity
Solution: Dioscin (15 μM) + Doxorubicin reduced HCC cell viability by 68% vs 45% mono-therapy
Outcome: Patent filed for combination therapy (WO2023017232)

Case 2: NutraHerb Co. (Germany)

Challenge: Develop joint health supplement with clinical evidence
Solution: 100 mg/day Dioscin in 12-week trial (n=120)
Outcome: 37% improvement in WOMAC scores vs placebo (p<0.01)

5. Request a Quote or Sample

Contact our experts for technical specifications, bulk pricing, or clinical trial support:

Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?
• ISO 9001-certified production
• Batch-to-batch consistency (HPLC reports provided)
• Custom synthesis up to 99.5% purity

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