Tosylmethyl Isocyanide (CAS 36635-61-7) Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 36635-61-7 |
| Molecular Formula | C9H9NO2S |
| Molecular Weight | 195.24 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage Conditions | 2-8°C in inert atmosphere |
Comparative Analysis
| Feature | Tosylmethyl Isocyanide | Conventional Isocyanides |
|---|---|---|
| Reactivity | High in Passerini reactions | Moderate |
| Stability | 6 months at proper storage | 3-4 months |
| Pharma Compatibility | GMP-grade available | Limited options |
2. Key Applications & Use Cases
Widely utilized in:
- Multi-component reactions (Ugi, Passerini)
- Anticancer drug intermediates synthesis
- Polymer cross-linking agents
- Asymmetric catalysis
3. Industrial Case Studies
Case Study 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Challenge: Low yield in kinase inhibitor synthesis
Solution: Implemented TMIC in Ugi-smile reaction
Result: 68% yield improvement, reduced side products
Case Study 2: Advanced Material Production
Client: European Polymer Manufacturer
Challenge: Unstable conductive polymer chains
Solution: Used TMIC as cross-linker agent
Result: 40% conductivity enhancement
4. Operational Guidelines
- Use under nitrogen atmosphere
- Recommended solvent: Dry DMF
- Optimal reaction temperature: 0-5°C
- Incompatible with strong oxidizers
5. Technical Comparison
| Vendor | Purity | Lead Time | Batch Consistency |
|---|---|---|---|
| Vendor A | 95% | 4 weeks | ±5% |
| Vendor B | 97% | 2 weeks | ±3% |
| Our Product | 99% | 1 week | ±1% |
6. Contact for Custom Solutions
Email: info@vivalr.com
Phone: (86) 15866781826
Request parameters:
– Required quantity
– Application details
– Purity requirements
– Preferred shipping method
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