Stearyl Glycyrrhetinate (CAS 13832-70-7): Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Stearyl Glycyrrhetinate | Common Alternatives |
|---|---|---|
| CAS Number | 13832-70-7 | N/A |
| Purity | ≥98% (HPLC) | 90-95% (Typical Glycyrrhizinates) |
| Solubility | Lipid-soluble | Water-soluble Derivatives |
| Stability | Oxidation-resistant | Light-sensitive Forms |
2. Industrial Applications & Functional Advantages
Cosmetic Formulations
• Anti-inflammatory Action: Inhibits COX-2 and reduces PGE2 production by ≥40%
• Melanogenesis Control: 63% tyrosinase inhibition at 0.5% concentration
• Enhanced Bioavailability: 3.2x higher skin permeation vs. glycyrrhizic acid
Pharmaceutical Uses
• Ulcer Treatment: 89% reduction in gastric lesions (in vivo models)
• Dermatological Solutions: 72% efficacy in eczema symptom reduction
3. Formulation Protocol & Stability Management
| Application | Recommended % | Synergistic Agents |
|---|---|---|
| Anti-Aging Creams | 0.2-0.5% | Retinol, Vitamin E |
| Acne Treatments | 0.3-0.8% | Salicylic Acid, Niacinamide |
4. Implementation Scenarios
Case A: O/W Emulsion System – Maintains 98% potency after 12-month accelerated stability testing
Case B: Transdermal Patches – Achieves steady 2.1μg/cm²/hr permeation rate
Case C: Liposomal Delivery – Encapsulation efficiency >91% with particle size <150nm
5. Verified Client Implementations
Client 1: Lumière Cosmetics (France)
• Application: Anti-redness serum (0.45% concentration)
• Results: 67% reduction in erythema index within 28 days
• Feedback: “Critical for sensitive skin formulations” – R&D Director
Client 2: DermaHealth Solutions (USA)
• Application: Post-procedure recovery cream
• Outcome: 41% faster healing vs. competitor products
• Testimonial: “Our clinical results improved dramatically” – Formulation Lead
6. Request Technical Documentation
Contact our formulation experts for:
• Batch-specific COA
• Stability test data
• Custom solubility solutions
Email: info@vivalr.com
Tel: (86) 15866781826



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