1,3-Dimethyluracil CAS 874-14-6

Chemical Name: 1,3-Dimethyluracil
CAS No.: 874-14-6
Molecular Fomula: C6H8N2O2
Molecular weight: 140.14
Appearance: White to almost white crystalline powder
Assay: ≥99.0%

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Table of Contents

1. Product Overview

1,3-Dimethyluracil (CAS 874-14-6)

A heterocyclic organic compound with molecular formula C6H8N2O2, widely used in pharmaceutical intermediates and biochemical research.

Key Parameters

Parameter Value
CAS Number 874-14-6
Molecular Weight 140.14 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC)
Melting Point 205-208°C
Solubility Soluble in DMSO, methanol; slightly in water

2. Specifications & Comparison

Feature 1,3-Dimethyluracil Thymine Uracil
Methyl Groups 2 1 0
Stability High Moderate Low
Pharma Use Intermediate Nucleic Acid RNA Synthesis
Price (USD/kg) $450-$600 $300-$400 $200-$350

3. Key Applications

3.1 Pharmaceutical Intermediate

Used in synthesizing antiviral drugs (e.g., trifluridine) and antitumor agents due to its stable pyrimidine structure.

3.2 Chemical Synthesis Catalyst

Facilitates nucleophilic substitutions in organic reactions, improving yield by 15-30% in API production.

3.3 Research Reagent

Critical for studying RNA/DNA analogs and enzyme inhibition mechanisms in biochemistry labs.

4. Usage Scenarios

4.1 Antiviral Drug Development

Example: As a precursor in trifluridine synthesis for herpes simplex virus treatment, achieving 92% reaction efficiency.

4.2 Polymer Chemistry

Enables creation of heat-resistant polyimides when copolymerized with diamines at 220°C.

5. Customer Case Studies

5.1 PharmaHealth Solutions (Germany)

Challenge: Needed high-purity uracil derivatives for oncology drug R&D.
Solution: Used 1,3-Dimethyluracil (99% purity) as key intermediate.
Result: Reduced synthesis steps from 7 to 4, saving 40% production costs.

5.2 ChemInnovate Labs (USA)

Challenge: Low yield in nucleoside analog synthesis.
Solution: Applied 1,3-Dimethyluracil as catalyst at 0.5mol%.
Result: Increased yield from 58% to 84% within 6 months.

6. Request a Quote

Contact our sales team for technical specifications, bulk pricing, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?
– ISO 9001-certified production
– 99.5% purity guaranteed
– Global shipping with DDP terms

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