4-Methoxytriphenylmethyl Chloride (CAS 14470-28-1) Comprehensive Guide
Table of Contents
- Product Overview
- Parameter Comparison with Similar Compounds
- Detailed Applications
- Usage Guidelines
- Case Studies
- Inquiry & Contact
Product Overview
4-Methoxytriphenylmethyl chloride (CAS 14470-28-1) is a specialized protecting agent widely used in organic synthesis. Key specifications include:
| Parameter | Value |
|---|---|
| CAS Number | 14470-28-1 |
| Molecular Formula | C20H17ClO |
| Molecular Weight | 308.80 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in airtight container |
Parameter Comparison with Similar Compounds
| Compound | CAS | Protecting Group Stability | Deprotection Condition |
|---|---|---|---|
| 4-Methoxytriphenylmethyl chloride | 14470-28-1 | High (acid-sensitive) | Mild acidic conditions |
| Trityl chloride | 76-83-5 | Moderate | Strong acids |
| MMTr chloride | 13139-88-3 | Very High | Specific reagent systems |
Detailed Applications
- Hydroxyl Group Protection: Selective protection in carbohydrate and nucleoside chemistry
- Oligonucleotide Synthesis: Key reagent in solid-phase DNA/RNA synthesis
- Pharmaceutical Intermediates: Critical for antiviral/anticancer drug development
Usage Guidelines
- Use anhydrous conditions for optimal reactivity
- Recommended solvent: Dichloromethane or THF
- Typical reaction temperature: 0-25°C
Case Studies
Case 1: Antiviral Drug Development
Client: European Pharma Company
Application: Nucleoside protection in Remdesivir analogue synthesis
Result: 92% yield improvement vs traditional methods
Case 2: Oligonucleotide Production
Client: US Biotech Firm
Application: RNA strand protection in mRNA vaccine components
Result: 99.7% purity achieved
Inquiry & Contact
For technical specifications or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
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