Chemical Name: 2,3,4-Trifluorobromobenzene
CAS No.: 176317-02-5
Molecular Fomula: C6H2BrF3
Molecular weight: 210.98
Appearance: Clear liquid
Assay: ≥98.0%
Parameter | Specification |
---|---|
CAS Number | 176317-02-5 |
Molecular Formula | C6H2BrF3 |
Molecular Weight | 211.98 g/mol |
Appearance | Clear colorless to pale yellow liquid |
Purity | ≥98.5% (GC) |
Boiling Point | 152-154°C at 760 mmHg |
Density | 1.698 g/cm³ at 25°C |
Refractive Index | n20/D 1.476 |
Flash Point | 46.7°C |
Storage Conditions | 2-8°C in inert atmosphere |
Property | 2,3,4-Trifluorobromobenzene | 2,4,5-Trifluorobromobenzene | 3,4,5-Trifluorobromobenzene |
---|---|---|---|
Reactivity | High para-directing | Moderate meta-directing | Low ortho-directing |
Pharma Compatibility | Excellent | Good | Fair |
Thermal Stability | Stable to 200°C | Stable to 180°C | Stable to 160°C |
Catalyst Response | Pd/C Compatible | Ni Catalyst Required | Specialty Catalysts |
Widely utilized in synthesizing fluorinated active pharmaceutical ingredients (APIs) including:
Used in continuous flow synthesis of moxifloxacin intermediates, achieving 92% yield improvement over traditional methods.
Implemented in semiconductor cleaning formulations, reducing particle contamination by 78% in 5nm chip production.
Parameter | Detail |
---|---|
Client Profile | Top 5 EU anticancer drug producer |
Application | Kinase inhibitor intermediate synthesis |
Implementation | Batch process optimization |
Result | 38% cost reduction, 15% purity increase |
Parameter | Detail |
---|---|
Client Profile | Global semiconductor manufacturer |
Application | Wafer cleaning solution additive |
Implementation | Precision formulation development |
Result | 0.5nm surface uniformity achieved |
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