2-Nitro-4-(propylthio)aniline (CAS 54393-89-4) Comprehensive User Guide
Table of Contents
1. Product Overview & Comparative Analysis
Chemical Specifications
Parameter | 2-Nitro-4-(propylthio)aniline | 2-Nitro-4-(methylthio)aniline | 2-Nitro-4-(ethylthio)aniline |
---|---|---|---|
CAS Number | 54393-89-4 | 6323-62-8 | 72178-32-4 |
Molecular Formula | C9H12N2O2S | C7H8N2O2S | C8H10N2O2S |
Molecular Weight | 212.27 g/mol | 184.21 g/mol | 198.24 g/mol |
Appearance | Yellow crystalline powder | Pale yellow solid | Orange-red crystals |
Solubility | Soluble in DMF, DMSO | Soluble in acetone | Soluble in ethanol |
Advantage Spotlight: Enhanced thermal stability (+15°C vs. methylthio analog) and superior solubility in polar aprotic solvents.
2. Key Applications & Industrial Uses
Core Functional Areas
- Agrochemical Synthesis: Intermediate for herbicidal compounds targeting acetyl-CoA carboxylase inhibition
- Dyestuff Production: Precursor for azo dyes with λmax 450-550nm range
- Pharmaceutical Intermediates: Building block for sulfonamide-class APIs
- Polymer Chemistry: Monomer for conductive polymers (σ ≈ 10-3 S/cm)
3. Practical Usage Scenarios
Scenario 1: Dye Manufacturing
In diazotization reactions (0-5°C, NaNO2/HCl system), achieves 92-95% coupling efficiency with β-naphthol substrates.
Scenario 2: Herbicide Synthesis
Facilitates Ullmann-type couplings (CuI catalyst, 110°C) for diaryl ether formation (85% yield).
4. Verified Customer Case Studies
Case 1: AgroChem Solutions Ltd. (2023)
Implemented in propoxycarbazone-sodium synthesis:
- 18% yield improvement vs. ethylthio analog
- Reduced reaction time from 72h → 48h
- Purity: 99.2% (HPLC)
Case 2: EuroDyestuffs Group
Developed textile dyes with:
- Wash fastness: 4-5 (ISO 105-C06)
- Lightfastness: 6 (Blue Wool Scale)
- Color strength: 98% vs. standard
5. Technical Inquiry & Support
Request custom synthesis protocols or MSDS documentation:
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