N-(4-cyano-phenyl)-glycine (CAS 42288-26-6) Comprehensive Guide
Table of Contents
Product Specifications & Comparative Analysis
| Parameter | N-(4-cyano-phenyl)-glycine | Analogous Compounds |
|---|---|---|
| CAS Registry | 42288-26-6 | N/A |
| Molecular Formula | C9H8N2O2 | C8H7NO2 (Phenylglycine) |
| Purity Grade | ≥98% (HPLC) | 95-97% (Standard analogs) |
| Thermal Stability | Stable ≤200°C | Decomposes at 160-180°C |
Key Applications & Industrial Uses
Pharmaceutical Synthesis: Critical intermediate in kinase inhibitor production and novel cancer therapeutics development.
Advanced Material Science: Precursor for conductive polymers in organic electronics applications.
Biochemical Research: Essential building block in peptide modification studies and enzyme activity analysis.
Operational Protocols & Best Practices
Storage Guidelines: Maintain under inert atmosphere at 2-8°C for long-term stability.
Reaction Optimization: Recommended pH range 6.5-7.5 for amide coupling reactions.
Safety Protocols: Mandatory PPE including nitrile gloves and chemical goggles during handling.
Documented Implementation Scenarios
Case 1: API synthesis for third-generation EGFR inhibitors (Scale: 500kg batch production)
Case 2: Conductive polymer development for flexible OLED displays (Research institution collaboration)
Enterprise Client Success Stories
Client A: Top 10 Pharma Company – Achieved 22% yield improvement in oncology drug intermediate synthesis through optimized glycine derivatives application.
Client B: National Research Laboratory – Developed high-efficiency organic photovoltaic materials using customized cyanophenyl-glycine formulations.
Technical Consultation & Procurement
Contact our chemical engineering specialists for:
- Custom synthesis scale-up solutions
- Regulatory compliance documentation
- Bulk pricing (100kg+ quantities)
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