Chemical Name: N-(4-cyano-phenyl)-glycine
Cas No.: 42288-26-6
Molecular Fomula: C9H8N2O2
Molecular Weight: 176.17
Appearance: White to light yellow powder
Parameter | N-(4-cyano-phenyl)-glycine | Analogous Compounds |
---|---|---|
CAS Registry | 42288-26-6 | N/A |
Molecular Formula | C9H8N2O2 | C8H7NO2 (Phenylglycine) |
Purity Grade | ≥98% (HPLC) | 95-97% (Standard analogs) |
Thermal Stability | Stable ≤200°C | Decomposes at 160-180°C |
Pharmaceutical Synthesis: Critical intermediate in kinase inhibitor production and novel cancer therapeutics development.
Advanced Material Science: Precursor for conductive polymers in organic electronics applications.
Biochemical Research: Essential building block in peptide modification studies and enzyme activity analysis.
Storage Guidelines: Maintain under inert atmosphere at 2-8°C for long-term stability.
Reaction Optimization: Recommended pH range 6.5-7.5 for amide coupling reactions.
Safety Protocols: Mandatory PPE including nitrile gloves and chemical goggles during handling.
Case 1: API synthesis for third-generation EGFR inhibitors (Scale: 500kg batch production)
Case 2: Conductive polymer development for flexible OLED displays (Research institution collaboration)
Client A: Top 10 Pharma Company - Achieved 22% yield improvement in oncology drug intermediate synthesis through optimized glycine derivatives application.
Client B: National Research Laboratory - Developed high-efficiency organic photovoltaic materials using customized cyanophenyl-glycine formulations.
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