Pyrrole-2-carbonitrile (CAS 4513-94-4) Comprehensive User Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Uses
- 3. Technical Parameter Comparison
- 4. Usage Scenarios & Best Practices
- 5. Verified Customer Case Studies
- 6. Request Customized Solutions
1. Product Overview & Specifications
Pyrrole-2-carbonitrile (CAS 4513-94-4) is a heterocyclic organic compound with molecular formula C5H4N2. Key parameters:
| Parameter | Value |
|---|---|
| Purity | ≥99% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 98-102°C |
| Storage Temp. | 2-8°C in inert atmosphere |
| Solubility | Soluble in DMF, DMSO; sparingly in water |
2. Key Applications & Industry Uses
Core Applications:
- Pharmaceutical intermediates for kinase inhibitors
- Building block in organic conductive polymers
- Precursor for corrosion inhibitors in metal treatment
- Agrochemical synthesis (herbicide intermediates)
3. Technical Parameter Comparison
| Feature | Pyrrole-2-carbonitrile | Similar Compounds |
|---|---|---|
| Reactivity | High (CN group activation) | Moderate (Pyrrole derivatives) |
| Thermal Stability | Stable below 150°C | Varies by substitution |
| Pharma Compatibility | FDA DMF filed | Limited documentation |
4. Usage Scenarios & Best Practices
Scenario 1: Pharmaceutical Synthesis
Used in 5-step synthesis of JAK2 inhibitors under nitrogen atmosphere at 0-5°C. Recommended stoichiometric ratio 1:1.2 with boronic acid partners.
Scenario 2: Polymer Production
Key monomer in polypyrrole conductive films. Optimal electropolymerization at 0.5M concentration in acetonitrile.
5. Verified Customer Case Studies
Case 1: Top 10 Pharma Company (2023)
- Application: Oncology drug intermediate
- Volume: 850kg batch order
- Result: Achieved 99.7% purity, reduced side reactions by 40%
Case 2: Advanced Materials Lab
- Usage: Conductive sensor development
- Technical Support: Custom particle size (50-100μm)
- Outcome: 15% improvement in electrical conductivity
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- GMP-grade manufacturing
- Custom synthesis derivatives
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