Pyrrole-2-carbonitrile Cas 4513-94-4

Chemical Name: PYRROLE-2-CARBONITRILE
CAS No.: 4513-94-4
Molecular Fomula: C5H4N2
Chemical Structure:

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Pyrrole-2-carbonitrile (CAS 4513-94-4) Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Pyrrole-2-carbonitrile (CAS 4513-94-4) is a heterocyclic organic compound with molecular formula C5H4N2. Key parameters:

Parameter Value
Purity ≥99% (HPLC)
Appearance White to off-white crystalline powder
Melting Point 98-102°C
Storage Temp. 2-8°C in inert atmosphere
Solubility Soluble in DMF, DMSO; sparingly in water

2. Key Applications & Industry Uses

Core Applications:

  • Pharmaceutical intermediates for kinase inhibitors
  • Building block in organic conductive polymers
  • Precursor for corrosion inhibitors in metal treatment
  • Agrochemical synthesis (herbicide intermediates)

3. Technical Parameter Comparison

Feature Pyrrole-2-carbonitrile Similar Compounds
Reactivity High (CN group activation) Moderate (Pyrrole derivatives)
Thermal Stability Stable below 150°C Varies by substitution
Pharma Compatibility FDA DMF filed Limited documentation

4. Usage Scenarios & Best Practices

Scenario 1: Pharmaceutical Synthesis

Used in 5-step synthesis of JAK2 inhibitors under nitrogen atmosphere at 0-5°C. Recommended stoichiometric ratio 1:1.2 with boronic acid partners.

Scenario 2: Polymer Production

Key monomer in polypyrrole conductive films. Optimal electropolymerization at 0.5M concentration in acetonitrile.

5. Verified Customer Case Studies

Case 1: Top 10 Pharma Company (2023)

  • Application: Oncology drug intermediate
  • Volume: 850kg batch order
  • Result: Achieved 99.7% purity, reduced side reactions by 40%

Case 2: Advanced Materials Lab

  • Usage: Conductive sensor development
  • Technical Support: Custom particle size (50-100μm)
  • Outcome: 15% improvement in electrical conductivity

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • GMP-grade manufacturing
  • Custom synthesis derivatives

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