2-Bromo-4-chloroaniline CAS 873-38-1

Chemical Name: 2-Bromo-4-chloroaniline
CAS No.: 873-38-1
Molecular Fomula:4C6H5BrClN
Molecular weight: 206.47
Appearance:Pale brown Powder

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2-Bromo-4-chloroaniline (CAS 873-38-1) Comprehensive Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Value Source Variation
CAS Number 873-38-1 Consistent across sources
Molecular Formula C₆H₅BrClN Consistent
Molecular Weight 206.47 g/mol 206.47–206.468
Density 1.7 g/cm³ ±0.1 tolerance
Melting Point 64–68°C Lit. range verified
Boiling Point 127°C (20 mmHg)
264.9°C (760 mmHg)
Pressure-dependent values
Flash Point 114°C ±21.8°C tolerance
HS Code 29214200 (EU) Customs classification

2. Applications & Industrial Uses

2-Bromo-4-chloroaniline serves as a critical intermediate in:

  • Pharmaceutical Synthesis: Building block for active pharmaceutical ingredients (APIs) targeting neurological disorders.
  • Agrochemical Production: Precursor in herbicide formulations, particularly chlorinated compound systems.
  • Material Science: Functionalization agent for specialty polymers with halogenated aromatic structures.

3. Practical Use Cases

Case 1: Pharmaceutical Intermediate

Used in multi-step synthesis of dopamine D2 receptor antagonists, enabling precise bromine-chlorine substitution patterns for enhanced bioactivity.

Case 2: Herbicide Development

Key component in protoporphyrinogen oxidase (PPO) inhibitor synthesis, contributing to broad-spectrum weed control solutions.

4. Client Success Stories

Nanjing Chemical Reagent Co., Ltd.

Integrated 2-Bromo-4-chloroaniline into their high-purity reagent line (98% GC), supporting academic research on halogenated aniline derivatives. Client reported 15% yield improvement in Suzuki coupling reactions.

Cangzhou Enke Pharmaceutical Technology

Supplied bulk quantities (≥99% purity) for GMP-compliant anticancer drug intermediates. Reduced production costs by 22% through optimized bromination-chlorination sequencing.

5. Inquiry & Procurement Guidance

For technical specifications, batch pricing, or regulatory documentation:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Include your required quantity, purity grade (98% GC standard or custom), and intended application for expedited service.

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