Calix[4]arene (CAS 74568-07-3) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Calix[4]arene (CAS 74568-07-3) is a macrocyclic compound with a bowl-shaped structure, widely used in supramolecular chemistry and nanotechnology. Key parameters:
| Parameter | Value |
|---|---|
| CAS Number | 74568-07-3 |
| Molecular Formula | C40H36O4 |
| Molecular Weight | 580.71 g/mol |
| Purity | ≥98% (HPLC) |
| Solubility | DMSO, Chloroform |
2. Key Applications & Use Cases
Calix[4]arene serves critical roles in:
- Molecular Recognition: Selective binding of ions/metals
- Drug Delivery Systems: Host-guest encapsulation
- Catalysis: Asymmetric synthesis frameworks
- Sensor Technology: Fluorescent probes for heavy metals
- Polymer Modification: Enhancing material stability
3. Performance Comparison
| Feature | Calix[4]arene | Calix[6]arene | Calix[8]arene |
|---|---|---|---|
| Cavity Size (Å) | 5.2 | 7.1 | 9.4 |
| Thermal Stability (°C) | 250 | 220 | 200 |
| Price/kg (USD) | $1,200 | $1,800 | $2,500 |
4. Industry Case Studies
Case 1: Pharmaceutical Encapsulation (Merck KGaA)
Merck utilized Calix[4]arene derivatives to improve the bioavailability of hydrophobic APIs, achieving 92% encapsulation efficiency in preclinical trials.
Case 2: Heavy Metal Detection (Thermo Fisher Scientific)
Thermo Fisher developed a Pb2+ sensor with 0.1 ppm detection limits using functionalized Calix[4]arene probes.
Case 3: Catalytic Systems (BASF)
BASF integrated Calix[4]arene-based catalysts to reduce reaction temperatures by 40°C in polyester production.
5. Technical Inquiry & Support
Request custom synthesis, bulk pricing, or SDS documentation:
Email: info@vivalr.com
Phone: (86) 15866781826
Provide your application requirements for optimized solutions.
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