Boron Trifluoride-Phenol Complex CAS 462-05-5

Chemical Name: Boron Trifluoride-Phenol Complex
CAS No.: 462-05-5
Molecular Fomula: C6H6BF3O
Molecular weight: 161.92
Appearance: Red or brown liquid
Assay: ≥25.0%

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Boron Trifluoride-Phenol Complex (CAS 462-05-5) User Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter BF3-Phenol Complex Conventional Lewis Acids Solid Acid Catalysts
CAS Number 462-05-5 Varies Varies
Appearance Colorless to pale yellow liquid Varied colors White/colored solids
Reaction Temperature -20°C to 80°C 50°C-150°C 100°C-300°C
Catalytic Efficiency High (85-95% yield) Moderate (60-75%) Variable (40-90%)

2. Key Applications & Industrial Uses

2.1 Organic Synthesis

Facilitates Friedel-Crafts reactions for:

  • Alkylation of aromatic compounds
  • Acylation processes in fine chemical production
  • Synthesis of pharmaceutical intermediates

2.2 Polymer Industry

  • Catalyst for cationic polymerization
  • Production of polyols and resins
  • Modification of polymer molecular structures

3. Operational Guidelines & Best Practices

3.1 Reaction Setup

  • Recommended dosage: 0.5-5 mol%
  • Optimal temperature range: 0-50°C
  • Moisture-sensitive – maintain dry environment

3.2 Safety Protocols

  • Use in fume hood with proper PPE
  • Storage: Dry inert atmosphere at 2-8°C
  • Neutralization procedure: 10% sodium bicarbonate solution

4. Case Study: Pharmaceutical Intermediate Synthesis

Client Profile

  • Company: MediChem Solutions Ltd.
  • Location: Basel, Switzerland
  • Industry: API Manufacturing

Implementation

  • Application: Synthesis of antihistamine intermediate
  • Process: BF3-mediated Friedel-Crafts acylation
  • Result: Yield increased from 68% to 89% vs. AlCl3

5. Case Study: Polymerization Catalyst in Petrochemicals

Client Profile

  • Company: PolyNova Energy Materials
  • Location: Houston, Texas, USA
  • Industry: Specialty Polymers

Implementation

  • Application: Cationic polymerization of isobutylene
  • Process: 0.8% BF3 complex in continuous reactor
  • Result: 92% conversion rate, Mw distribution ±1.2

6. Technical Consultation & Ordering Process

For technical specifications or bulk orders:

Our chemical engineers will provide:

  • Customized catalytic system design
  • Process optimization consulting
  • Technical documentation (SDS, COA)
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