2,2,2-Trifluoroethyl Trifluoromethanesulfonate (CAS 6226-25-1): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2,2,2-Trifluoroethyl Trifluoromethanesulfonate (CAS 6226-25-1) is a highly reactive fluorinated sulfonic ester widely used in advanced organic synthesis. Key specifications include:
| Parameter | Details |
|---|---|
| Chemical Formula | C3H2F6O3S |
| Purity | ≥99% (HPLC) |
| Packaging | Sealed bags (10g–1kg) / Drums (5–25kg) |
| Storage | 2–8°C in inert atmosphere |
| HS Code | 2905599890 (UK/EU) |
2. Key Applications & Industrial Uses
This compound serves as a critical building block in:
- Pharmaceutical Intermediates: Synthesis of fluorinated APIs (Antiviral/anticancer agents)
- Advanced Materials: Fluoropolymer modification for enhanced chemical resistance
- Catalysis: Lewis acid catalyst in asymmetric synthesis
- Electrolyte Additives: High-performance lithium-ion battery formulations
3. Performance Comparison with Alternatives
| Feature | Trifluoroethyl Triflate | Methyl Triflate | Ethyl Triflate |
|---|---|---|---|
| Reactivity | High | Moderate | Low |
| Fluorine Content | 55.8% | 37.2% | 29.6% |
| Thermal Stability | Stable ≤150°C | Stable ≤100°C | Stable ≤80°C |
4. Practical Use Cases
Case Study A: Antiviral Drug Intermediate
Used in 3-step synthesis of Remdesivir analogs, achieving 92% yield with 99.5% enantiomeric excess.
Case Study B: Fluorinated Polymer Production
Key monomer in weather-resistant coating formulations for aerospace applications.
5. Client Success Stories
Shanghai Yubo Biotechnology
Integrated this compound into their API production line, reducing synthesis steps by 40% while maintaining GMP compliance.
Aladdin Scientific
Utilized as a specialty reagent in custom fluorination services for semiconductor material development.
6. Request a Quote
For pricing, technical data sheets, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Batch certification and COA available upon request.
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