4-boric acid pinacol ester-9, 9-dimethyl fluorene CAS 1365692-79-0

Chemical Name:  4-boric acid pinacol ester-9, 9-dimethyl fluorene
CAS No.: 1365692-79-0
Molecular Fomula: C21H25BO2
Molecular weight: 320.23
Appearance: Crystal or crystalline powder

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Comprehensive Guide to 4-Boric Acid Pinacol Ester-9,9-Dimethyl Fluorene (CAS 1365692-79-0)

Table of Contents

Product Overview

4-Boric Acid Pinacol Ester-9,9-Dimethyl Fluorene (CAS 1365692-79-0) is a high-purity organoboron compound widely used in cross-coupling reactions, pharmaceutical intermediates, and advanced material synthesis. Its unique fluorene backbone enhances stability and reactivity in demanding chemical environments.

Specifications & Comparative Analysis

Parameter Specification Standard Boronic Esters
Molecular Formula C₂₁H₂₃BO₂ Varies by structure
Purity ≥98.5% (HPLC) Typically 95-97%
Storage Conditions 2-8°C under inert gas Room temperature
Thermal Stability Stable up to 200°C Degrades at 150-170°C

Key Applications

Pharmaceutical Synthesis

Enables precise Suzuki-Miyaura couplings for:

  • Anticancer drug intermediates
  • Kinase inhibitor frameworks
  • PET tracer precursors

Advanced Material Development

  • OLED charge transport layers
  • Polymer-supported catalysts
  • Supramolecular architectures

Industry Case Studies

Case Study 1: Oncology Drug Development

Client: Top 10 Global Pharma Company

Challenge: Improve yield in Bruton’s tyrosine kinase inhibitor synthesis

Solution: Implemented CAS 1365692-79-0 in key coupling step

Result: 42% yield increase vs. traditional boronic acids

Case Study 2: OLED Manufacturing

Client: Display Materials Innovator

Requirement: Stable electron transport material for flexible displays

Outcome: Achieved 15% efficiency gain with modified fluorene system

Contact for Technical Consultation

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