1-Propyl-1H-imidazole CAS 35203-44-2

Chemical Name: 1-Propyl-1H-imidazole
CAS No.: 35203-44-2
Molecular Fomula: C6H10N2
Molecular weight: 110.16
Appearance: Colorless to light yellow transparent liquid
Assay: ≥99.0%

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1-Propyl-1H-imidazole (CAS 35203-44-2) Comprehensive User Guide

1. Product Specifications & Comparative Analysis

Parameter 1-Propyl-1H-imidazole Conventional Imidazoles
Chemical Formula C6H10N2 Varies by substitution
Molecular Weight 110.157 g/mol 90-130 g/mol
Appearance Colorless to pale yellow liquid Typically colorless
Density 0.95 g/cm³ 0.9-1.1 g/cm³
Boiling Point 221.3°C @ 760 mmHg 200-250°C
Flash Point 87.6°C 80-100°C
Purity Grade Pharmaceutical (≥99%) Industrial (95-98%)

2. Industrial Applications

Core Functional Roles:

  • Pharmaceutical Synthesis: Key intermediate in ACE inhibitors and antiviral agents
  • Polymer Chemistry: Co-monomer in specialty polyimide production
  • Coordination Chemistry: Ligand precursor for transition metal catalysts
  • Ionic Liquid Formulations: Base component for low-viscosity solvents

3. Operational Guidelines

Handling Protocols:

  • Storage: Maintain under nitrogen atmosphere at 2-8°C
  • Reactivity: Avoid strong oxidizers and mineral acids
  • PPE Requirements: Chemical-resistant gloves + vapor respirator
  • Waste Management: Neutralize with 5% acetic acid before disposal

4. Implementation Case Studies

Case 1: Pharmaceutical Intermediate Production

Application: Synthesis of antihypertensive API
Result: 18% yield improvement vs. traditional methods

Case 2: Specialty Polymer Development

Application: High-temperature polyimide film
Result: Achieved 320°C continuous operating temperature

5. Client Success Stories

Client A: Global Pharmaceutical Manufacturer

Challenge: Scale-up of antiviral compound
Solution: Optimized alkylation process using 1-propylimidazole
Outcome: Achieved 95% purity at metric ton scale

Client B: Advanced Materials Producer

Challenge: Develop flexible OLED substrates
Solution: Incorporated as crosslinking agent
Outcome: 40% improvement in thermal stability

6. Technical Consultation

Contact our chemical engineering specialists for:
– Custom synthesis parameters
– Regulatory compliance guidance
– Application-specific formulation support

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