Ethanesulfonyl Chloride CAS 594-44-5

Chemical Name: Ethanesulfonyl Chloride
Synonyms: 1-Ethanesulfonyl chloride
CAS No.:  594-44-5
Molecular Fomula: C2H5ClO2S
Molecular weight: 128.58
Appearance: Colorless to light yellow liquid
Assay: ≥99%

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Ethanesulfonyl Chloride CAS 594-44-5: Comprehensive User Guide

1. Product Overview & Specifications

CAS Number: 594-44-5
Molecular Formula: C2H5ClO2S
Molecular Weight: 144.58 g/mol
Appearance: Clear colorless to pale yellow liquid
Purity: ≥98% (GC)
Boiling Point: 220°C
Density: 1.406 g/cm3 at 25°C

Comparative Analysis

Parameter Ethanesulfonyl Chloride Methanesulfonyl Chloride Benzenesulfonyl Chloride
Reactivity High Moderate Low
Thermal Stability Stable up to 200°C Stable up to 180°C Decomposes at 150°C

2. Key Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesizing sulfonamide antibiotics and antiviral agents through nucleophilic substitution reactions.

Agrochemical Production

Key component in creating sulfonylurea herbicides, enhancing crop protection efficiency by 40-60% compared to traditional methods.

3. Industrial Case Studies

Case Study 1: API Manufacturing

Client: Top 10 Global Pharma Company
Challenge: Low yield (52%) in sulfonation step
Solution: Optimized Ethanesulfonyl Chloride ratio (1:1.2 molar ratio)
Result: Yield increased to 89% with 99.5% purity

Case Study 2: Specialty Chemicals

Client: European Chemical Manufacturer
Application: Dye intermediate synthesis
Outcome: Reduced reaction time from 8hr to 2.5hr at 80°C

4. Competitive Advantages

Feature Ethanesulfonyl Chloride Alternatives
Storage Stability 24 months under nitrogen 6-12 months
Byproduct Formation <3% 8-15%

5. Request Technical Support

Email: info@vivalr.com
Phone: (86) 15866781826

Request MSDS, COA, or custom synthesis protocols today.

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