Diethyl Acetamidomalonate (CAS 1068-90-2) Buyer’s Guide
Contents
- Product Specifications & Comparative Analysis
- Key Applications & Industrial Uses
- Operational Best Practices
- Industry Application Scenarios
- Client Implementation Case Studies
- Request Customized Solutions
Product Specifications & Comparative Analysis
| Parameter | Diethyl Acetamidomalonate | Similar Esters |
|---|---|---|
| CAS Number | 1068-90-2 | Varies by compound |
| Molecular Formula | C9H15NO5 | Typically C7-11H12-18NO4-6 |
| Purity Grade | ≥99% (Pharmaceutical Grade) | 90-98% (Industrial Grade) |
| Thermal Stability | Stable up to 200°C | 160-180°C range |
Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical precursor for antiviral medications (e.g., Cidofovir analogs) and oncology drugs (Gemcitabine derivatives).
Peptide Synthesis: Enables production of non-natural amino acids for advanced drug formulations.
Agrochemical Development: Used in creating targeted pesticide molecules with improved biodegradability.
Operational Best Practices
Storage: Maintain in sealed containers at 2-8°C under nitrogen atmosphere
Reaction Optimization: Recommended molar ratios 1:1.2 with carbonyl compounds in THF/DMF solvent systems
Safety Protocols: Use PPE with vapor concentration monitoring below 5 ppm
Industry Application Scenarios
Antiviral Drug Production: Key intermediate in nucleoside analog synthesis for HCV/HIV treatments
Oncology Research: Enables creation of platinum-based chemotherapy agent precursors
Advanced Material Science: Building block for conductive polymer development
Client Implementation Case Studies
Case 1: European Pharma Manufacturer (2023)
– Application: Large-scale production of Brincidofovir intermediates
– Results: Achieved 92% yield improvement through optimized malonate activation
– Client Feedback: “Superior batch consistency reduced our QC costs by 18%”
Case 2: Asian Agrochem Leader (2024)
– Application: Novel insect growth regulator development
– Results: Enabled 40% reduction in synthetic steps compared to traditional methods
– Technical Note: Implemented continuous flow chemistry integration
Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ quantities)
- Custom synthesis protocols
- Regulatory support documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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