Methotrexate Disodium Salt (CAS 7413-34-5) Product Guide
Table of Contents
1. Basic Information & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 7413-34-5 |
| Molecular Formula | C₂₀H₂₀N₈Na₂O₅ |
| Molecular Weight | 498.4 g/mol |
| Appearance | Yellow to light yellow powder |
| Purity | ≥98% (HPLC) |
| Solubility | Water-soluble |
| Storage | 4°C, sealed, away from light |
2. Detailed Applications
- Antimetabolite Therapy: Inhibits dihydrofolate reductase, blocking DNA synthesis in rapidly dividing cells
- Oncology Research: Key component in acute lymphoblastic leukemia (ALL) treatment protocols
- Immunosuppression: FDA-approved for rheumatoid arthritis management
- Dermatology: Off-label use in severe psoriasis treatment
- Chemical Biology: Tool compound for folate pathway studies
3. Usage Case Studies
Case Study 1: Hematological Research Center
Application: ALL treatment protocol optimization
Dosage: 12 mg/m² weekly administration
Outcome: Achieved 78% remission rate in Phase II trials
Case Study 2: Autoimmune Disease Clinic
Application: Refractory rheumatoid arthritis management
Protocol: 7.5-25 mg weekly subcutaneous injection
Result: 62% reduction in disease activity score (DAS28)
Case Study 3: Pharmaceutical Development
Use: Reference standard in generic drug formulation
Specification: ≥99% purity requirement
Validation: Successful bioequivalence testing per FDA guidelines
4. Supplier Comparison
| Supplier | Purity | Packaging | Price Range |
|---|---|---|---|
| Sinnhu Biological | 98% | 1g, 5g | $40-$110 |
| MedChemExpress | 99.71% | 20mg | $255 |
| Yuanye Bio | 98% | 200mg | $192 |
5. Contact for Quotation
For technical specifications or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Availability: Commercial and research-grade quantities
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