Holo-Transferrin (CAS 11096-37-0) Comprehensive Product Guide
Table of Contents
Product Specifications & Comparative Analysis
| Parameter | Holo-Transferrin | Apo-Transferrin |
|---|---|---|
| CAS Number | 11096-37-0 | 11096-36-9 |
| Molecular Formula | C75H121N23O28S | C74H119N23O28S |
| Molecular Weight | 1824.97 g/mol | 1802.94 g/mol |
| Iron Saturation | ≥98% | ≤5% |
| Storage Conditions | 2-8°C in lyophilized form | |
Key Biological Applications
Essential for cellular iron transport and metabolism regulation:
- Enhances thrombin enzymatic activity (effective at 0.2-5μM concentrations)
- Facilitates iron-dependent cell proliferation in serum-free media
- Critical component in mammalian cell culture systems
- Regulates oxidative stress through iron ion chelation
Operational Protocols & Usage Guidelines
Recommended implementation parameters:
| Application | Concentration Range | Incubation Time |
|---|---|---|
| Cell Culture Supplement | 5-50 μg/mL | Continuous exposure |
| Enzyme Activation | 0.2-5 μM | 30-60 minutes |
| Drug Delivery Systems | 1-10 mg/mL | Variable by formulation |
Industry Application Case Studies
Case 1: Biopharmaceutical Production Optimization
Implemented in CHO cell lines showed 42% yield improvement through iron metabolism regulation.
Case 2: Neurodegenerative Research
Demonstrated iron chelation efficiency in Parkinson’s disease models at 10μM concentrations.
Verified Client Implementations
Client 1: BioGen Therapeutics (2024)
Utilized in monoclonal antibody production scale-up, achieving GMP compliance.
Client 2: Shanghai Institute of Cell Biology (2025)
Critical component in novel cancer immunotherapy development.
Technical Consultation & Procurement
Contact our protein specialists for technical specifications or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
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