Loratadine CAS 79794-75-5: Comprehensive User Guide
Table of Contents
1. Product Information & Specifications
Loratadine (CAS 79794-75-5) is a second-generation antihistamine widely used to treat allergies. Below are its key specifications:
| Parameter | Specification |
|---|---|
| Chemical Name | Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate |
| CAS Number | 79794-75-5 |
| Molecular Formula | C22H23ClN2O2 |
| Molecular Weight | 382.88 g/mol |
| Appearance | White crystalline powder |
Comparative Advantages
- Non-sedating: Unlike first-gen antihistamines, Loratadine does not cause drowsiness.
- Long-lasting: 24-hour relief with a single dose.
- Low drug interactions: Minimal metabolism via CYP450 enzymes.
2. Detailed Applications of Loratadine
Loratadine is primarily used for:
- Allergic Rhinitis: Reduces sneezing, nasal congestion, and itching.
- Chronic Urticaria: Manages hives and skin inflammation.
- Off-label Uses: Adjunct therapy for allergic asthma and conjunctivitis.
Formulation Types
- Tablets (10 mg)
- Oral syrup (1 mg/mL)
- Rapid-dissolving tablets
3. Usage Cases & Scenarios
Case 1: Seasonal Allergy Management
Scenario: A 35-year-old patient with pollen allergies uses Loratadine 10 mg daily during spring. Symptoms (sneezing, itchy eyes) reduce within 1 hour, with no drowsiness reported.
Case 2: Chronic Urticaria Management
Scenario: A clinical study showed 80% of patients achieved complete hive resolution after 2 weeks of Loratadine therapy.
4. Real Client Case Studies
Client 1: PharmaCorp Inc. (USA)
- Challenge: Needed a cost-effective API for OTC allergy medication.
- Solution: Sourced Loratadine CAS 79794-75-5 with 99.8% purity.
- Result: 30% reduction in production costs; FDA approval achieved in 6 months.
Client 2: HealthPlus Distributors (EU)
- Challenge: Required stable Loratadine supply for pediatric syrup.
- Solution: Provided batch-tested raw material with ISO certification.
- Result: 95% customer satisfaction; zero quality complaints in 12 months.
5. Request a Quote or Sample
Contact us for pricing, COA, or bulk orders:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Why Choose Us?
- GMP-certified manufacturing
- 99.5% minimum purity guarantee
- Global shipping with cold-chain support



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