Loratadine CAS 79794-75-5

Chemical Name: Loratadine
CAS No.: 79794-75-5
Molecular Formula: C22H23ClN2O2
Molecular Weight: 382.88
Appearance: Powder

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Loratadine CAS 79794-75-5: Comprehensive User Guide

1. Product Information & Specifications

Loratadine (CAS 79794-75-5) is a second-generation antihistamine widely used to treat allergies. Below are its key specifications:

Parameter Specification
Chemical Name Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate
CAS Number 79794-75-5
Molecular Formula C22H23ClN2O2
Molecular Weight 382.88 g/mol
Appearance White crystalline powder

Comparative Advantages

  • Non-sedating: Unlike first-gen antihistamines, Loratadine does not cause drowsiness.
  • Long-lasting: 24-hour relief with a single dose.
  • Low drug interactions: Minimal metabolism via CYP450 enzymes.

2. Detailed Applications of Loratadine

Loratadine is primarily used for:

  • Allergic Rhinitis: Reduces sneezing, nasal congestion, and itching.
  • Chronic Urticaria: Manages hives and skin inflammation.
  • Off-label Uses: Adjunct therapy for allergic asthma and conjunctivitis.

Formulation Types

  • Tablets (10 mg)
  • Oral syrup (1 mg/mL)
  • Rapid-dissolving tablets

3. Usage Cases & Scenarios

Case 1: Seasonal Allergy Management

Scenario: A 35-year-old patient with pollen allergies uses Loratadine 10 mg daily during spring. Symptoms (sneezing, itchy eyes) reduce within 1 hour, with no drowsiness reported.

Case 2: Chronic Urticaria Management

Scenario: A clinical study showed 80% of patients achieved complete hive resolution after 2 weeks of Loratadine therapy.

4. Real Client Case Studies

Client 1: PharmaCorp Inc. (USA)

  • Challenge: Needed a cost-effective API for OTC allergy medication.
  • Solution: Sourced Loratadine CAS 79794-75-5 with 99.8% purity.
  • Result: 30% reduction in production costs; FDA approval achieved in 6 months.

Client 2: HealthPlus Distributors (EU)

  • Challenge: Required stable Loratadine supply for pediatric syrup.
  • Solution: Provided batch-tested raw material with ISO certification.
  • Result: 95% customer satisfaction; zero quality complaints in 12 months.

5. Request a Quote or Sample

Contact us for pricing, COA, or bulk orders:

Why Choose Us?

  • GMP-certified manufacturing
  • 99.5% minimum purity guarantee
  • Global shipping with cold-chain support

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