Polycarbophil (CAS 9003-97-8): Comprehensive Technical Overview
Table of Contents
1. Basic Parameters & Comparative Analysis
| Parameter | Polycarbophil | Calcium Polycarbophil |
|---|---|---|
| CAS Number | 9003-97-8 | 9003-97-8 |
| Molecular Formula | (C20H18Ca4O18)n | |
| Appearance | White powder | |
| Water Absorption | ~1000× volume expansion | pH-dependent swelling |
| Density | 1.4±0.1 g/cm³ | – |
| Refractive Index | 1.618 | – |
2. Functional Applications
Medical Applications
- Sodium-sensitive patient care: Primary treatment for chronic constipation in cases of hypertension, edema, and congestive heart failure
- Antidiarrheal agent: Water absorption capacity regulates stool consistency
Mechanism of Action
Exhibits pH-responsive hydrogel formation (pH >4-6) through carboxylate group ionization, creating electrostatic repulsion that enables volumetric expansion up to 1000× original size.
3. Pharmaceutical Specifications
| Grade | Purity | Packaging | Regulatory Compliance |
|---|---|---|---|
| USP29 | ≥99% | 25kg fiber drums | Pharmaceutical-grade |
| Industrial | 95-98% | Custom packaging | GMP standards |
4. Industrial Suppliers
Certified Manufacturers
| Supplier | Location | Production Capacity | Lead Time |
|---|---|---|---|
| Qingyuan Shengyi Biotechnology Co. | Guangdong, China | 50MT/month | 3-5 business days |
| Zhejiang Wuyi Jiayuan Pharmaceutical Materials | Zhejiang, China | 30MT/month | 7-10 business days |
5. Inquiry Guidance
For technical specifications, regulatory documentation, or customized formulations:
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