Tributyltin Hydride Cas 688-73-3

Chemical Name: Tributyltin Hydride
Synonyms: Tri-n-butyltin; Tributylstannane
CAS No.: 688-73-3
Molecular Formula: C12H28Sn
Molecular Weight: 291.06

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Table of Contents

1. Product Overview & Specifications

Tributyltin Hydride (CAS 688-73-3)

Parameter Specification
Chemical Formula C12H27Sn
Molecular Weight 291.06 g/mol
Appearance Colorless to pale yellow liquid
Density 1.082 g/mL at 25°C
Boiling Point 281.5±9.0°C
Flash Point 124.0±18.7°C
Storage 2-8°C under inert atmosphere
Purity ≥97% (with 0.05% BHT stabilizer)

Comparative Analysis

Feature Tributyltin Hydride Alternative Reductants
Reaction Selectivity High stereochemical control Moderate to low
Thermal Stability Stable below 40°C Variable
Byproduct Formation Minimal tin residues Significant side products

2. Key Applications

Core Functional Uses

  • Radical-Mediated Reductions: Selective dehalogenation of organic compounds
  • Cyclization Reactions: Formation of 5-7 membered rings in complex molecules
  • Polymer Modification: Controlled chain termination in organotin catalysis
  • Pharmaceutical Intermediates: Synthesis of chiral centers in API development

Industry-Specific Implementations

  • Agrochemicals: Production of tin-containing fungicides
  • Electronics: Precursor for conductive polymer synthesis
  • Advanced Materials: Surface modification of nanoparticles

3. Industrial Use Cases

Case Study 1: Pharmaceutical Synthesis

A leading research institute utilized Tributyltin Hydride for the stereoselective synthesis of Taxol side chains, achieving 92% yield with >99% enantiomeric excess through radical-mediated hydrogen transfer.

Case Study 2: Polymer Chemistry

In controlled radical polymerization processes, the compound enabled precise molecular weight distribution (PDI <1.2) for specialty silicone rubbers used in medical devices.

4. Client Implementation Examples

Client A: Specialty Chemicals Manufacturer

  • Application: Continuous flow synthesis of organotin catalysts
  • Outcome: 40% reduction in reaction time with 99.5% purity
  • Volume: 500kg/month production scale

Client B: Contract Research Organization

  • Application: Radiolabeled compound preparation
  • Result: Successful 119Sn NMR tracking of reaction pathways
  • Regulatory: Achieved ICH Q3D elemental impurity guidelines

5. Contact for Technical Consultation

For bulk pricing, SDS documentation, or custom synthesis requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

Request product samples or schedule a process optimization review with our chemists.

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