Trichloroacetonitrile (CAS 545-06-2) Comprehensive User Guide
Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Uses
- 3. Performance Comparison With Alternatives
- 4. Operational Guidelines & Best Practices
- 5. Verified Customer Case Studies
- 6. Request Customized Solutions
1. Product Overview & Specifications
Trichloroacetonitrile (CAS 545-06-2) is a halogenated nitrile compound with molecular formula C3Cl3N. Key technical parameters:
| Parameter | Value |
|---|---|
| Purity Grade | ≥99.5% (Industrial Grade) |
| Boiling Point | 84-86°C at 20 mmHg |
| Flash Point | 72°C (Closed Cup) |
| Density | 1.48 g/cm³ at 25°C |
| Vapor Pressure | 2.1 mmHg at 20°C |
| Storage Conditions | 2-8°C in airtight containers |
2. Key Applications & Industry Uses
Primary industrial applications include:
- Pharmaceutical intermediates synthesis
- Agrochemical production (herbicides/pesticides)
- Organic synthesis catalyst
- Chemical warfare agent detection systems
- Polymer modification agent
3. Performance Comparison With Alternatives
| Feature | Trichloroacetonitrile | Acetonitrile | Chloroacetonitrile |
|---|---|---|---|
| Reactivity | High | Moderate | Medium-High |
| Thermal Stability | Excellent | Good | Fair |
| Solubility in Water | 0.8 g/L | Miscible | 3.2 g/L |
| LD50 (Oral Rat) | 238 mg/kg | 2460 mg/kg | 140 mg/kg |
4. Operational Guidelines & Best Practices
Critical handling protocols:
- Use NIOSH-approved respirators above 50°C
- Maintain inert atmosphere during transfer operations
- Implement secondary containment for bulk storage
- Neutralize spills with 10% sodium carbonate solution
5. Verified Customer Case Studies
Case 1: Agrochemical Manufacturer (Germany)
- Challenge: Develop next-gen soil fumigant with lower environmental impact
- Solution: Used as key intermediate in trifluoromethylpyridine synthesis
- Result: 40% reduction in production steps vs traditional methods
Case 2: Pharmaceutical Research Lab (USA)
- Challenge: Create novel HIV protease inhibitor candidates
- Solution: Served as cyano-group donor in ring-forming reactions
- Result: Achieved 92% reaction yield under optimized conditions
6. Request Customized Solutions
Contact our chemical engineering team for technical support:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request bulk pricing, SDS documentation, or custom synthesis projects.



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