Polyquaternium-1 (CAS 75345-27-6) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification | Comparison with Similar Polymers |
|---|---|---|
| CAS Number | 75345-27-6 | Unique identifier for pharmaceutical-grade quaternary ammonium compounds |
| Molecular Formula | (C6H12N)NC16H36N2O6·3Cl | Higher chlorine content vs standard polyquats for enhanced antimicrobial action |
| Appearance | Amber to dark brown solid | Lower coloration than standard cationic polymers |
| Molecular Weight | 6500-57,000 Da (polymer range) | Broader MW distribution for multifunctional applications |
| pH Stability | 6.0-9.0 | Wider effective range than BAK derivatives |
2. Key Applications
Pharmaceutical Uses
- Primary preservative in ophthalmic solutions (eye drops)
- Antimicrobial agent in topical formulations
- Excipient for controlled drug delivery systems
Industrial Applications
- Active component in contact lens cleaning solutions
- Antistatic agent in polymer production
- Biocide in personal care products
3. Usage Guidelines
Recommended Concentrations
| Application | Concentration Range | Processing Temperature |
|---|---|---|
| Eye Care Products | 0.001-0.01% w/v | 20-25°C |
| Contact Lens Solutions | 0.005-0.05% w/v | RT to 40°C |
4. Industry Case Studies
Case 1: Ophthalmic Solution Manufacturer
Challenge: Reduce preservative-related ocular irritation in artificial tears
Solution: Implemented 0.005% Polyquaternium-1 as primary biocide
Result: 62% reduction in patient-reported irritation vs BAK-preserved formulas
Case 2: Contact Lens Care System
Challenge: Improve protein removal in multipurpose solutions
Solution: 0.03% Polyquaternium-1 with enzymatic cleaner
Result: 89% lysozyme removal efficiency maintained over 30-day cycle
5. Inquiry & Contact
For technical specifications sheets, bulk pricing, and formulation support:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
| Lead Time | 3-5 business days for samples 2-4 weeks for bulk orders |
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