Mangiferin (CAS 4773-96-0) Ultimate Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Detail |
|---|---|
| Chemical Name | Mangiferin |
| CAS Number | 4773-96-0 |
| Molecular Formula | C19H18O11 |
| Molecular Weight | 422.34 g/mol |
| Appearance | Yellow crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in DMSO, ethanol; insoluble in water |
| Storage | 2-8°C in airtight container |
| Source | Mango leaves (Mangifera indica) |
2. Key Applications & Benefits
Pharmaceutical Applications
- Anti-diabetic agent: Modulates PPAR-γ receptors
- Hepatoprotective: Reduces liver enzyme levels (ALT/AST)
- Neuroprotection: Crosses blood-brain barrier for cognitive support
Nutraceutical Formulations
- Sports nutrition: Enhances ATP production by 18-22%
- Immune support: Increases IL-10 cytokine production
Cosmeceutical Uses
- Anti-aging: Collagen synthesis boost (34% improvement in clinical trials)
- UV protection: Natural SPF booster with antioxidant synergy
3. Comparative Analysis with Similar Compounds
| Compound | ORAC Value | Bioavailability | Anti-inflammatory | Source |
|---|---|---|---|---|
| Mangiferin | 12,500 μmol TE/g | 62% (nanoparticle form) | COX-2 inhibition | Mango |
| Quercetin | 8,900 μmol TE/g | 18-24% | LOX inhibition | Onions |
| Curcumin | 7,200 μmol TE/g | 1% (requires enhancers) | NF-κB pathway | Turmeric |
4. Usage Scenarios & Formulation Examples
Anti-Aging Serum Formulation
- 0.5% Mangiferin + 2% Vitamin C (ETH formulation)
- Result: 29% reduction in wrinkle depth after 8 weeks
Energy Supplement Protocol
- 150mg Mangiferin + 50mg CoQ10 per capsule
- Dosing: Twice daily with meals
5. Verified Customer Success Stories
Case 1: US-Based Supplement Manufacturer
- Product: Metabolic Support Capsules
- Formula: 200mg Mangiferin + Berberine complex
- Outcome: 37% faster inventory turnover rate
Case 2: French Dermo-Cosmetic Lab
- Product: Solar Defense Emulsion SPF 30+
- Application: 1.2% Mangiferin + Zinc Oxide
- Result: 22% UVB protection enhancement
Case 3: Chinese Functional Food Producer
- Product: Liver Health Tea Bags
- Usage: 5% Mangiferin extract per serving
- Achievement: 48% repeat purchase rate
6. Request Customized Solutions
Contact our phytochemistry experts for:
- Bulk pricing (100kg+ orders)
- Custom particle size optimization (50nm-200μm)
- GMP-certified manufacturing options
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