1. Product Overview & Specification Comparison

Chemical Profile

3-Hydroxypyrazine-2-Carboxamide (CAS 55321-99-8) is a specialized heterocyclic compound with molecular formula C₅H₅N₃O₂. This white to off-white crystalline powder is soluble in DMSO and methanol, with a purity grade of ≥98% (HPLC).

Specification Comparison Table

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Primarily used in synthesizing antituberculosis agents like Ethambutol, enabling precise molecular modifications through its reactive hydroxyl and carboxamide groups.

Research Applications

• Building block for kinase inhibitor development
• Ligand in coordination chemistry studies
• Precursor for functionalized pyrazine derivatives

3. Step-by-Step Usage Guidelines

1. Storage: Maintain at 2-8°C in sealed containers under inert gas
2. Handling: Use PPE including nitrile gloves and safety goggles
3. Solubilization: Warm DMSO to 40°C for optimal dissolution
4. Reaction: Employ under nitrogen atmosphere for oxygen-sensitive reactions

4. Practical Application Scenarios

Case 1: Antitubercular Drug Synthesis

Used in Step 3 of Ethambutol HCl production, achieving 92% reaction yield under optimized conditions (pH 7.4, 65°C).

5. Verified Customer Case Studies

6. Contact for Technical Consultation

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