2-Naphthylboronic Acid (CAS 32316-92-0): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
2-Naphthylboronic Acid (CAS 32316-92-0) is a high-purity organoboron compound widely used in Suzuki-Miyaura cross-coupling reactions. Its molecular formula is C10H9BO2, with a molecular weight of 172.0 g/mol.
| Parameter | Specification |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 210-215°C |
| Storage | 2-8°C in airtight container |
2. Key Applications & Use Cases
2.1 Pharmaceutical Intermediates
Used in synthesizing kinase inhibitors and anticancer agents due to its stable boronic ester formation.
2.2 OLED Material Synthesis
Critical for creating naphthalene-based electron transport layers in organic LEDs.
2.3 Agrochemistry
Employed in developing herbicides with selective action mechanisms.
3. Performance Comparison
| Compound | Reactivity | Stability | Cost Efficiency |
|---|---|---|---|
| 2-Naphthylboronic Acid | High | Excellent | $$$ |
| Phenylboronic Acid | Moderate | Good | $$ |
4. Industry Case Studies
Case 1: Pharmaceutical Manufacturer (Shanghai)
Challenge: Required high-yield synthesis of Bruton’s tyrosine kinase (BTK) inhibitor intermediates.
Solution: Implemented 2-Naphthylboronic acid in palladium-catalyzed coupling reactions.
Result: Achieved 92% reaction yield with >99% chiral purity.
Case 2: OLED Materials Supplier (Shenzhen)
Challenge: Needed thermally stable hole-blocking materials.
Solution: Developed naphthacene derivatives using 2-Naphthylboronic acid.
Result: Increased device lifetime by 40% compared to conventional materials.
5. Request Customized Solutions
Our technical team specializes in boronic acid derivative applications. Contact us for:
- Bulk pricing (1kg to ton-scale quantities)
- Custom purity specifications (up to 99.9%)
- Technical documentation (COA, MSDS, NMR spectra)
Email: info@vivalr.com
Tel: (86) 15866781826
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