3-Isobutyl-1-Methylxanthine CAS 28822-58-4

Chemical Name: 3-Isobutyl-1-Methylxanthine
Cas No.: 28822-58-4
Appearance: White Powder
Assay:≥99.0%

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3-Isobutyl-1-Methylxanthine (CAS 28822-58-4) User Guide: Applications, Case Studies & SEO-Optimized Insights

1. Product Overview & Specifications

3-Isobutyl-1-Methylxanthine (CAS 28822-58-4) is a xanthine derivative widely used in biochemical research and pharmaceutical development. Below are its key specifications:

Parameter Details
Chemical Name 3-Isobutyl-1-Methylxanthine
CAS Number 28822-58-4
Molecular Formula C9H14N4O2
Molecular Weight 210.23 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Solubility Soluble in DMSO, ethanol; slightly soluble in water

Comparative Analysis

Feature 3-Isobutyl-1-Methylxanthine Similar Compounds (e.g., Caffeine)
PDE Inhibition High selectivity Broad-spectrum
Solubility Limited in aqueous solutions Higher water solubility
Research Applications Fat cell studies, neuroprotection Stimulant research

2. Key Applications & Industrial Uses

2.1 Biochemical Research

  • Phosphodiesterase (PDE) Inhibition: Modulates cAMP levels in adipocytes for obesity/diabetes studies.
  • Fat Cell Differentiation: Critical in 3T3-L1 cell line protocols.

2.2 Pharmaceutical Development

  • Bronchodilator Formulations: Synergistic use with β-agonists for asthma/COPD.
  • Neuroprotective Agents: Reduces neuronal apoptosis in Parkinson’s/Alzheimer’s models.

3. Step-by-Step Usage Guidelines

3.1 Preparation

  1. Dissolve in DMSO at 50 mM stock concentration.
  2. Dilute in cell culture medium to 0.5-1 mM working concentration.

3.2 Safety Protocols

  • Store at 2-8°C in airtight containers.
  • Use PPE (gloves, goggles) during handling.

4. Real-World Case Studies

4.1 Case Study 1: Adipogenesis Research

Client: University of California, San Francisco
Application: 3T3-L1 differentiation protocol
Result: 80% differentiation efficiency at 0.75 mM concentration.

4.2 Case Study 2: Neuroprotection Trials

Client: Harvard Medical School
Application: MPTP-induced Parkinson’s model
Result: 40% reduction in dopaminergic neuron loss.

5. Inquiry & Contact Information

Request custom formulations or bulk quotes:
Email: info@vivalr.com
Phone: (86) 15866781826

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