Pinacolborane (CAS 25015-63-8) Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Pinacolborane | Alternative Boron Reagents |
|---|---|---|
| CAS Number | 25015-63-8 | Varies by product |
| Molecular Formula | C6H13BO2 | Depends on composition |
| Molecular Weight | 127.98 g/mol | Typically 100-150 g/mol |
| Boiling Point | 42-43°C (50 mmHg) 109.9°C (760 mmHg) |
Generally higher volatility |
| Flash Point | 5°C (closed cup) | Variable, often higher |
| Density | 0.882 g/cm3 | 0.8-1.2 g/cm3 |
2. Key Applications
Core Functional Uses:
- Hydroboration Reactions: Enables efficient boron addition to alkenes/alkynes under mild conditions
- Cross-Coupling Catalysis: Essential for Suzuki-Miyaura reactions with Pd/Rh/Ni catalysts
- Pharmaceutical Intermediates: Critical in synthesizing boronic ester derivatives
- Polymer Chemistry: Facilitates controlled polymer chain growth
3. Operational Guidelines
Recommended Practices:
- Store at 2-8°C under inert atmosphere (N2 or Ar)
- Use explosion-proof equipment below 5°C flash point
- Implement strict moisture control (reacts violently with H2O)
- Employ PPE: chemical goggles, neoprene gloves, vapor respirator
4. Case Studies
| Application | Conditions | Yield |
|---|---|---|
| Vinyl Boronate Synthesis | RhCl(PPh3)3, THF, 25°C | 92% |
| Aryl Coupling Reaction | Pd(OAc)2, SPhos, K3PO4 | 87% |
5. Client Success Stories
Pharmaceutical Innovator (Shanghai)
- Achieved 40% reduction in catalyst loading
- Scaled boronic ester production to metric ton scale
Advanced Materials Developer (Wuhan)
- Enabled synthesis of novel OLED materials
- Improved reaction selectivity to >95%
6. Request a Quote
Contact our technical specialists for bulk pricing, SDS, or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826
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