1. Product Overview & Specifications

2,5-Dibromopyridine (CAS 624-28-2) is a brominated pyridine derivative widely used in pharmaceuticals, agrochemicals, and material science. Key specifications include:

Comparative Analysis

2,5-Dibromopyridine offers distinct advantages over similar compounds:

2. Applications & Use Cases

Pharmaceutical Intermediates

Used in synthesizing antiviral and anticancer drugs due to its bromine substitution pattern, enabling precise functionalization.

Organic Synthesis

Key reagent in Suzuki-Miyaura couplings and Buchwald-Hartwig aminations for constructing complex heterocycles.

Agrochemicals

Intermediate in herbicides and insecticides, leveraging its stability under harsh conditions.

3. Step-by-Step Usage Examples

Example 1: Suzuki Coupling Reaction

1. Mix 2,5-Dibromopyridine (1 eq) with boronic acid (1.2 eq) in degassed toluene.
2. Add Pd(PPh₃)₄ (5 mol%) and Na₂CO₃ (2 eq).
3. Heat at 90°C for 12 hours under N₂.
4. Purify via column chromatography (yield: 85–92%).

4. Real Customer Case Studies

Case 1: ABC Pharmaceuticals

Application: Synthesis of a kinase inhibitor for oncology research.
Result: Achieved 95% purity, reducing downstream purification costs by 30%.

Case 2: XYZ Agrochemicals

Application: Development of a bromine-containing herbicide.
Result: Enhanced bioactivity by 40% compared to chloro analogues.

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